tag:blogger.com,1999:blog-6824624937303007277.comments2023-07-04T05:22:46.640-06:00Steve Koch ResearchSteve Kochhttp://www.blogger.com/profile/09076719001132389463noreply@blogger.comBlogger52125tag:blogger.com,1999:blog-6824624937303007277.post-62734944302677508152019-08-23T18:12:15.663-06:002019-08-23T18:12:15.663-06:00Irrespective of receiving daily oral or future inj...Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,psoriasis,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer,siva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Scoliosis,Brain Tumor,Fibromyalgia,Fluoroquinolone Toxicity<br />Syndrome Fibrodysplasia Ossificans ProgresSclerosis,Alzheimer's disease,Adrenocortical carcinoma Infectious mononucleosis. .Asthma,Allergic diseases.Hiv_ Aids,Herpe ,Copd,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Alzheimer's disease,<br />Dementia.(measles, tetanus, whooping cough, tuberculosis, polio and diphtheria),Chronic Diarrhea,<br />Hpv,All Cancer Types,Diabetes,Hepatitis,I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com / . even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man. Jesus Mckinneyhttps://www.blogger.com/profile/07413818374302186081noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-91968294853320607002019-08-23T18:12:07.289-06:002019-08-23T18:12:07.289-06:00Irrespective of receiving daily oral or future inj...Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,psoriasis,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer,siva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Scoliosis,Brain Tumor,Fibromyalgia,Fluoroquinolone Toxicity<br />Syndrome Fibrodysplasia Ossificans ProgresSclerosis,Alzheimer's disease,Adrenocortical carcinoma Infectious mononucleosis. .Asthma,Allergic diseases.Hiv_ Aids,Herpe ,Copd,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Alzheimer's disease,<br />Dementia.(measles, tetanus, whooping cough, tuberculosis, polio and diphtheria),Chronic Diarrhea,<br />Hpv,All Cancer Types,Diabetes,Hepatitis,I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com / . even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man. Jesus Mckinneyhttps://www.blogger.com/profile/07413818374302186081noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-58037543379349911902019-08-23T18:11:58.532-06:002019-08-23T18:11:58.532-06:00Irrespective of receiving daily oral or future inj...Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,psoriasis,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer,siva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Scoliosis,Brain Tumor,Fibromyalgia,Fluoroquinolone Toxicity<br />Syndrome Fibrodysplasia Ossificans ProgresSclerosis,Alzheimer's disease,Adrenocortical carcinoma Infectious mononucleosis. .Asthma,Allergic diseases.Hiv_ Aids,Herpe ,Copd,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Alzheimer's disease,<br />Dementia.(measles, tetanus, whooping cough, tuberculosis, polio and diphtheria),Chronic Diarrhea,<br />Hpv,All Cancer Types,Diabetes,Hepatitis,I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com / . even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man. Jesus Mckinneyhttps://www.blogger.com/profile/07413818374302186081noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-32676708260631706342019-08-23T18:10:44.613-06:002019-08-23T18:10:44.613-06:00Irrespective of receiving daily oral or future inj...Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Parkinson's disease,Schizophrenia,Lung Cancer,Breast Cancer,psoriasis,Colo-Rectal Cancer,Blood Cancer,Prostate Cancer,siva.Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,Desmoplastic small-round-cell tumor Diabetes ,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Ataxia,Arthritis,Amyotrophic Lateral Scoliosis,Brain Tumor,Fibromyalgia,Fluoroquinolone Toxicity<br />Syndrome Fibrodysplasia Ossificans ProgresSclerosis,Alzheimer's disease,Adrenocortical carcinoma Infectious mononucleosis. .Asthma,Allergic diseases.Hiv_ Aids,Herpe ,Copd,Glaucoma., Cataracts,Macular degeneration,Cardiovascular disease,Lung disease.Enlarged prostate,Osteoporosis.Alzheimer's disease,<br />Dementia.(measles, tetanus, whooping cough, tuberculosis, polio and diphtheria),Chronic Diarrhea,<br />Hpv,All Cancer Types,Diabetes,Hepatitis,I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com / . even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man. Jesus Mckinneyhttps://www.blogger.com/profile/07413818374302186081noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-26058373168614820122018-04-18T00:45:32.280-06:002018-04-18T00:45:32.280-06:00This information is very useful. thank you for sha...This information is very useful. thank you for sharing. and I will also share information about health through the website<br /><br /><a href="http://qncjellygamat20.blogspot.co.id/2018/03/cara-mengobati-cacingan-pada-anak.html" rel="nofollow">Cara Mengobati Cacingan</a><br /><a href="http://qncjellygamat20.blogspot.co.id/2018/03/obat-benjolan-di-belakang-telinga.html" rel="nofollow">Obat Benjolan di Belakang Telinga</a><br /><a href="http://www.obatscabies.com/pengobatan-alternatif-penyakit-hepatitis/" rel="nofollow">Pengobatan Alternatif Penyakit Hepatitis</a><br /><a href="http://www.obatscabies.com/obat-tradisional-cedera-lutut-keseleo-lutut/" rel="nofollow">Obat Tradisional Cedera Lutut/Keseleo Lutut</a><br /><a href="http://www.obatscabies.com/obat-penambah-berat-badan-alami-paling-ampuh/" rel="nofollow">Obat Penambah Berat Badan Alami</a><br /><a href="https://kumparan.com/halima-nur/obat-tradisional-radang-tenggorokan" rel="nofollow">Obat Tradisional Radang Tenggorokan</a><br />___________________Cara Mengatasi Sakit Perut saat Haidhttp://www.obatscabies.com/cara-mengatasi-sakit-perut-saat-haid/noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-79472705624039839102016-01-09T16:26:33.161-07:002016-01-09T16:26:33.161-07:00I wonder if you still have it, but can you please ...I wonder if you still have it, but can you please share the rejected proposal again? The Scribd link you mentioned in the post does not seem to work. Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-58309350888843353132013-08-21T08:41:30.821-06:002013-08-21T08:41:30.821-06:00Great blog post.Really looking forward to read mor...Great blog post.Really looking forward to read more.<br />Rapid Writershttp://www.rapidwriters.net/noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-36989032025241607422012-02-14T11:38:05.193-07:002012-02-14T11:38:05.193-07:00Steve, just recieved the official email confirming...Steve, just recieved the official email confirming the award. thanks for starting a blog on this topic...Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-53852266827341730102011-11-30T18:19:13.096-07:002011-11-30T18:19:13.096-07:00That is great news! Let us know when you receive t...That is great news! Let us know when you receive the news for sure & will be curious to know what the research is. Congratulations!Steve Kochhttps://www.blogger.com/profile/09076719001132389463noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-40283433317703724382011-11-30T15:28:41.505-07:002011-11-30T15:28:41.505-07:00Steve, I just got call from my program manager and...Steve, I just got call from my program manager and mentioned that my career proposal is recommended for funding; but emphasized that the conversation is not award notification. I am hoping that this is coming my way! I visited this blog several times in last years whenever I was emotionally down when my proposal was declined two times before...Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-46764339813379648422011-08-01T19:18:09.430-06:002011-08-01T19:18:09.430-06:00Here is a link to my 2011 NSF CAREER disaster http...Here is a link to my 2011 NSF CAREER disaster http://stevekochresearch.blogspot.com/2011/08/2011-nsf-career-proposal-ugh-failures.htmlSteve Kochhttps://www.blogger.com/profile/09076719001132389463noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-37882414232575611342011-07-24T12:36:07.946-06:002011-07-24T12:36:07.946-06:00It turns out in his 1934 Science paper (which as o...It turns out in his 1934 Science paper (which as of July 2011 is not indexed correctly on Web of Science), Gilbert Lewis specifically calls for experiments with deuterium-depleted water to see whether life forms have adapted a need for D in normal cellular operations. "It is not inconceivable that heavy hydrogen, which exists in small amounts in all natural water, may actually be essential to some plants or animals. A supply of water almost completely freed from the heavy isotope is now being prepared for the purpose of conducting such studies." [1] Despite ending his Science paper with these sentences, I could not find any follow-up to these studies! Neither by Lewis and colleagues, nor by any other groups in the following 75 years--except for the half dozen publications on Pub Med studying deuterium-depleted water in whole mammals or mammalian tissue culture.<br /><br />[1] Lewis, G. N. (1934). THE BIOLOGY OF HEAVY WATER. Science (New York, N.Y.), 79(2042), 151-153. doi: 10.1126/science.79.2042.151.Steve Kochhttps://www.blogger.com/profile/09076719001132389463noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-4837342588644499742011-01-25T09:38:04.299-07:002011-01-25T09:38:04.299-07:00Steve:
I just found that my career is declined. I...Steve:<br /><br />I just found that my career is declined. It was "highly recommended" by the panel with ratings: Excellent/Very Good, Very Good, Excellent, and Very Good. This was my second submission.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-52650631987628517782011-01-24T18:28:44.598-07:002011-01-24T18:28:44.598-07:00I just saw that the status date is changed but the...I just saw that the status date is changed but the status is still "pending". No calls nothing from PD. Seems like mine is shredded this time too.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-39722241210254384292011-01-20T19:58:45.106-07:002011-01-20T19:58:45.106-07:00hmmmm..... still no status change on my career pro...hmmmm..... still no status change on my career proposal.... still showing "pending" with status date of submission.... its exactly six months now.... looks like they are going to decline mine this time too...Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-32738932625459089532010-12-14T21:20:48.286-07:002010-12-14T21:20:48.286-07:00Hey Anonymous -- Good Luck!!! Don't be 100% s...Hey Anonymous -- Good Luck!!! Don't be 100% sure if you don't hear before Christmas. I know someone who found out very late like months into this year they were funded. Sometimes money comes in.<br /><br />As for us, we did not submit last year. The project, since it is not funded, has been very slow and we are still struggling for the necessary preliminary data. I decided that waiting another year made the most sense, and I think we will make it this year. Lots of hard work ahead, but much progress has been made, and some bad broken equipment problems overcome too.<br /><br />OK, Good luck, and come back and post when you find out the good news!Steve Kochhttps://www.blogger.com/profile/09076719001132389463noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-53181549900831296542010-12-14T21:10:21.743-07:002010-12-14T21:10:21.743-07:00Steve, I am here again after a year... i am waitin...Steve, I am here again after a year... i am waiting for my NSF CAREER results... this is the resubmitted version of the last submission... i was told that if the proposal is selected the the program manager will make a call before Christmas, if not then need to be prepared for decline notice in Feb-March...Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-22877742707198351952010-09-04T23:50:04.000-06:002010-09-04T23:50:04.000-06:00I remember hearing of testing whether a sample of ...I remember hearing of testing whether a sample of water was D2O by placing a tadpole in it.It was on a radio program, 'Jack Armstrong.'Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-78401331892516497592010-06-14T14:25:50.699-06:002010-06-14T14:25:50.699-06:00Can we use DPL lists with version mediawiki 1.4.6?...Can we use DPL lists with version mediawiki 1.4.6?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-22022939188273937002010-03-03T08:13:24.302-07:002010-03-03T08:13:24.302-07:00Hey Diego, Thanks for pointing out that I didn'...Hey Diego, Thanks for pointing out that I didn't link to the newer version on the 2008 Scribd page. I added a link on the Scribd page.<br /><br />I wrote the new (2009) version in NIH format. For the 2008 version, I had intentionally not done that because some people had advised me that NSF will not fund NIH-fundable projects. I mistakenly took this to mean I shouldn't write it in that format. But that was a very bad idea, because all the people on the review panel write and / or review NIH proposals and so, they're used to the Specific Aims, Background, Preliminary, etc. <br /><br />Combined with some simplifications, the new format was a big hit with the panel. They didn't say this explicitly, but the new reviews showed that they "got it," loved the project -- just wanted a lot more preliminary data, which is very fair. (They basically worry that I'm incompetent, showing no published results after 3 years, which, again, is fair...and correctable.) So, we have a couple months to do this and then I think we have a good shot at getting it funded!<br /><br />Here's the <a href="http://www.scribd.com/doc/17548381/2009-ProposalCAREER-SingleMolecule-Analysis-of-Genomic-DNA-and-Chromatin-in-Eukaryotic-Transcription" rel="nofollow">2009 version</a>.Steve Kochhttps://www.blogger.com/profile/09076719001132389463noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-8370707442318022092010-03-03T04:00:35.349-07:002010-03-03T04:00:35.349-07:00Wow, you have over 1000 reads for this proposal! W...Wow, you have over 1000 reads for this proposal! Were you planning on sharing the updated proposal? <br /><br />You touched on this and I'm sure that you made changes since then, but even with some background knowledge about the project, it seemed a little dense for me. That probably comes with the territory of molecular genetics (those darn abbreviations), but I would think that it would be a little easier to read by narrowing it down a bit. It sounds like this was a good experience for you (and for all of your readers) though. Best of luck in your new submissions!Diegohttps://www.blogger.com/profile/05341749485519153050noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-18349257135851815902010-02-18T14:23:35.506-07:002010-02-18T14:23:35.506-07:00My NSF CAREER proposal to Bio-DBI is still pending...My NSF CAREER proposal to Bio-DBI is still pending. Is it normal that it takes so long?Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-84623349362682826542010-02-06T20:42:17.191-07:002010-02-06T20:42:17.191-07:00Anonymous: Everyone I have spoken with who has exp...Anonymous: Everyone I have spoken with who has experience with the CAREER award (either applying or on review panels) has shared the opinion that there is heavy favoritism towards people in their 3rd and final submission. Furthermore, sometimes the review panels from one year to the next share many members. So, there is memory in those regards. <br /><br />In my case, I don't think there was any bias because it was not my third try. I had serious deficiencies. However, in your case, if everything seemed perfect and it was your first try (or second), I would not be discouraged. Just try to improve it a bit next time and for sure submit all three times. I have seen some really good proposals turned down on their 2nd attempt and then funded on 3rd attempt without much changed.Steve Kochhttps://www.blogger.com/profile/09076719001132389463noreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-80930239195340304142010-02-05T22:09:01.252-07:002010-02-05T22:09:01.252-07:00I am sorry to learn that your proposal was not fun...I am sorry to learn that your proposal was not funded. I guess such setbacks are part of our profession. I was very hopeful about my proposal. I spent almost 5 months just on one career proposal. I still feel that this is the best proposal I could write. Anyways, I am going to resubmit it. Its going to be tough requesting new support letters again. Since NSF doesnt have "memory" of the previous submissions/reviews, it is hard to be hopeful.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-6824624937303007277.post-54387387109746275942010-02-05T18:48:59.849-07:002010-02-05T18:48:59.849-07:00Yes, I did submit, and I decided to go completely ...Yes, I did submit, and I decided to go completely "open science" with it. I was declined again. The panel loved the open science! So, if it's appropriate for your field, I'd recommend including open science in your broader impacts. I will edit the bottom of the blogpost above to put some links in to my 2009 experience.<br /><br /><br />Good luck with your 2010 submission!<br /><br />--SteveSteve Kochhttps://www.blogger.com/profile/09076719001132389463noreply@blogger.com